| Generation New Era
DARS-NIC-782449-Z6G3F |
2 |
4 |
14 August 2026 to 16 February 2030 |
In term |
Yes |
| Generation New Era
DARS-NIC-792066-B5D2T |
1 |
2 |
14 August 2026 to 16 February 2030 |
In term |
Yes |
| Generation New Era - Phase 1a and 1b
DARS-NIC-800961-W7P2T |
2 |
3 |
17 February 2026 to 16 February 2030 |
In term |
Yes |
| Health, education and social outcomes of children with visual impairment and blindness (VI/SVIBL) - SHINE study
DARS-NIC-787209-F3W7J |
7 |
0 |
6 February 2026 to 5 February 2030 |
In term |
No |
| STAMPEDE trial: Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy (consent)
DARS-NIC-59873-D8C6G |
3 |
49 |
9 March 2026 to 30 June 2029 |
In term |
Yes |
| STAMPEDE trial: Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy (s251)
DARS-NIC-798687-Z0Z8F |
3 |
1 |
9 March 2026 to 30 June 2029 |
In term |
Yes |
| CMR predictors of mortality in patients undergoing Surgical AVR or TAVI for severe AS: The BSCMR Aortic Stenosis Outcome Study.
DARS-NIC-796232-C6B3Q |
3 |
19 |
1 March 2026 to 30 March 2029 |
In term |
No |
| Stratifying Genomic Causes of Intellectual Disability by Mental Health Outcomes in Childhood and Adolescence (IMAGINE-2)
DARS-NIC-168879-K2N8Q |
6 |
206 |
31 December 2025 to 8 January 2029 |
In term |
No |
| British Regional Heart Study - follow-up of the BRHS cohort
DARS-NIC-148411-Q64H8 |
7 |
89 |
18 February 2026 to 20 December 2028 |
In term |
No |
| British Regional Heart Study (BRHS)- linkage of established cohort to NHS England datasets (HES, MHMDS, DIDS)
DARS-NIC-28591-H5Q3X |
10 |
422 |
29 January 2026 to 20 December 2028 |
In term |
No |
| Cancer long-term follow-up study of clinical trial participants
DARS-NIC-779200-S6R2D |
4 |
34 |
5 December 2025 to 4 December 2028 |
In term |
Yes |
| The role of IAPT in the prevention of dementia and the amelioration of its impact on service use and co-morbidities (the MODIFY project)
DARS-NIC-157211-T8B2M |
16 |
808 |
7 November 2025 to 6 November 2028 |
In term |
No |
| United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)
DARS-NIC-334952-R5M7K |
11 |
40 |
13 October 2025 to 12 October 2028 |
In term |
Yes |
| Assessing the utility of healthcare systems data for trials: data utility comparisons in the STAMPEDE trial (DUCkS)(previously: ODR1718_094)
DARS-NIC-656801-R9F6Z |
10 |
18 |
13 October 2025 to 12 October 2028 |
In term |
Yes |
| Investigating the association between prenatal exposure to air pollution and maternal and child health outcomes
DARS-NIC-746266-S8M6T |
2 |
17 |
13 October 2025 to 12 October 2028 |
In term |
No |
| OPTICAL: Optimising Paediatric Transition to Intensive Care for AduLts
DARS-NIC-772633-Y3K3T |
7 |
77 |
3 October 2025 to 2 October 2028 |
In term |
No |
| Using electronic health records and continuous intra-cardiac electrogram monitoring to understand cardiovascular outcomes in patients with pacemakers and defibrillators (NICOR - 25 NCR 01)
DARS-NIC-787195-R1H2P |
8 |
48 |
29 September 2025 to 28 September 2028 |
In term |
No |
| Children and Families Policy Research Unit
DARS-NIC-393510-D6H1D |
22 |
607 |
8 September 2025 to 7 September 2028 |
In term |
No |
| Database of UK recipients of pituitary-derived human growth hormone
DARS-NIC-691697-K9L9B |
6 |
71 |
1 August 2025 to 31 July 2028 |
In term |
No |
| Understanding excess child and adolescent mortality in the UK
DARS-NIC-141410-W6H4Y |
10 |
76 |
14 February 2025 to 11 May 2028 |
In term |
No |
| Inequalities in cancer care pathways
DARS-NIC-777554-J2V4K |
3 |
4 |
29 April 2026 to 8 May 2028 |
In term |
No |
| MRC National Survey of Health and Development (NSHD) - tracing
DARS-NIC-774097-J9J0C |
1 |
2 |
31 March 2025 to 30 March 2028 |
In term |
No |
| AspECT EXceL- Aspirin Esomeprazole Chemoprevention Trial- Consenting Subset of the Cohort
DARS-NIC-644891-N5T3S |
3 |
3 |
21 February 2025 to 20 February 2028 |
In term |
No |
| AspECT EXceL- Aspirin Esomeprazole Chemoprevention Trial- Section 251 Subset of the Cohort
DARS-NIC-776114-J7Q9J |
3 |
3 |
21 February 2025 to 20 February 2028 |
In term |
No |
| 1970 British Cohort Study - Tracing
DARS-NIC-129836-D5F3W |
1 |
4 |
7 February 2025 to 6 February 2028 |
In term |
No |
| National Child Development Study (NCDS)- Tracing
DARS-NIC-137864-T1P9B |
2 |
8 |
7 February 2025 to 6 February 2028 |
In term |
No |
| Next Steps Cohort Study- Tracing
DARS-NIC-15226-X7Z9R |
6 |
25 |
7 February 2025 to 6 February 2028 |
In term |
No |
| Millennium Cohort Study (also known as Child of the New Century) - Tracing
DARS-NIC-408892-F1R1Y |
1 |
6 |
7 February 2025 to 6 February 2028 |
In term |
No |
| Vivaldi Social Care
DARS-NIC-769062-G5F1K |
5 |
188 |
25 May 2026 to 31 December 2027 |
In term |
No |
| SUMMIT Study: Cancer screening study with or without low-dose lung CT to validate a multi-cancer early detection test (Previously ODR1718_316)
DARS-NIC-656813-F4H5W |
10 |
199 |
20 December 2022 to 19 December 2027 |
In term |
Yes |
| EVenti: The Prognostic Performance of the Enhanced Liver Fibrosis Test in UK Patients with Chronic Liver Disease Assessed 20 Years After Recruitment to the EUROGOLF study (EVenti).
DARS-NIC-414309-R7H4W |
7 |
82 |
13 December 2024 to 12 December 2027 |
In term |
Yes |
| The impact of reimbursement schemes on healthcare providers' operational performance
DARS-NIC-727610-S2V3N |
1 |
0 |
22 October 2024 to 21 October 2027 |
In term |
No |
| Outcomes of septal reduction surgery in paediatric hypertrophic cardiomyopathy in the United Kingdom (23 CONG 01)
DARS-NIC-778853-K4R8H |
3 |
0 |
22 October 2025 to 21 October 2027 |
In term |
No |
| Childhood outcomes after perinatal brain injury (Data flowing to ONS)
DARS-NIC-342322-Q1N7M |
9 |
190 |
12 July 2024 to 17 October 2027 |
In term |
No |
| Childhood Outcomes after Perinatal Brain Injury (Data flowing to DfE)
DARS-NIC-475526-F3Z5H |
1 |
1 |
12 July 2024 to 17 October 2027 |
In term |
No |
| OLIVE: Improving the early detection of lung cancer in never-smokers
DARS-NIC-740806-W2F6Q |
3 |
4 |
13 March 2026 to 12 September 2027 |
In term |
No |
| A mixed methods evaluation of the National Perioperative Screening and Optimisation Programme (NPSOP) on patient centred outcomes- using the Hospital Episode Statistics
DARS-NIC-756900-Q2J3K |
3 |
0 |
5 June 2026 to 24 August 2027 |
In term |
No |
| General Health Outcomes in Subfertile Men: a UK register-based cohort study
DARS-NIC-692254-N3J5W |
6 |
79 |
1 August 2024 to 31 July 2027 |
In term |
No |
| Extended follow-up of the TARGIT A Trial
DARS-NIC-126676-G1X4M |
6 |
23 |
12 July 2024 to 11 July 2027 |
In term |
No |
| MR1179 - INFANT study
DARS-NIC-147793-R05H3 |
2 |
9 |
4 July 2012 to 4 July 2027 |
In term |
No |
| Whitehall II
DARS-NIC-346693-F2X1G |
19 |
264 |
5 July 2024 to 4 July 2027 |
In term |
No |
| Centre for Longitudinal Studies Birth Cohort Studies Data Linkage: National Child Development Study
DARS-NIC-49297-Q7G1Q |
8 |
77 |
24 May 2024 to 23 May 2027 |
In term |
No |
| Centre for Longitudinal Studies Birth Cohort Studies Data Linkage: 1970 British Cohort Study
DARS-NIC-49826-T0J7C |
7 |
77 |
24 May 2024 to 23 May 2027 |
In term |
No |
| Centre for Longitudinal Studies Next Steps Data Linkage: Next Steps Age 25 Study
DARS-NIC-51342-V1M5W |
8 |
105 |
24 May 2024 to 23 May 2027 |
In term |
No |
| Centre for Longitudinal Studies - Millennium Cohort Study (MCS)- (Age 17 consent)
DARS-NIC-384504-N2V5B |
5 |
70 |
10 May 2024 to 9 May 2027 |
In term |
No |
| Centre for Longitudinal Studies - Millennium Cohort Study (MCS) - Child of the New Century -Mortality
DARS-NIC-147860-0RSHN |
8 |
23 |
8 May 2026 to 7 May 2027 |
In term |
No |
| Camden & Islington Clinical Record Interactive Search (CRIS) Linkage with HES/Mortality Data
DARS-NIC-408171-X7F8W |
6 |
19 |
23 February 2026 to 2 May 2027 |
In term |
No |
| Education and Child Health Insights from Linked Data (The ECHILD Research Database)
DARS-NIC-381972-Q5F0V |
17 |
905 |
13 March 2026 to 31 March 2027 |
In term |
No |
| Centre for Longitudinal Studies -1970 British Cohort Study-Mortality
DARS-NIC-17218-B0W9X |
7 |
20 |
16 March 2026 to 27 March 2027 |
In term |
No |
| Centre for Longitudinal Studies -Next Steps Study - Mortality
DARS-NIC-431565-K9V9N |
2 |
4 |
16 March 2026 to 27 March 2027 |
In term |
No |
| MR1a - Health and Development Study - Consented Cohort Members
DARS-NIC-148100-6RFK9 |
12 |
121 |
17 October 2024 to 8 March 2027 |
In term |
No |
| Virus Watch: Understanding community incidence, symptom profiles, and transmission of COVID-19 in relation to population movement and behaviour
DARS-NIC-372269-N8D7Z |
10 |
56 |
6 October 2025 to 28 February 2027 |
In term |
No |
| General Health & Hospital Admissions in Children Born after ART; A Population Based Linkage Study
DARS-NIC-180665-GJMW5 |
6 |
1 |
26 February 2024 to 25 February 2027 |
In term |
No |
| Centre for Longitudinal Studies- National Child Development Study 1958 (NCDS)
DARS-NIC-147922-T7W2F |
8 |
69 |
20 February 2026 to 19 February 2027 |
In term |
No |
| Evaluating the Family Nurse Partnership in England
DARS-NIC-136916-B7D5C |
7 |
2 |
24 January 2024 to 23 January 2027 |
In term |
No |
| MR1b - Health and Development Study - S251 Cohort members
DARS-NIC-86954-Y0R2N |
11 |
63 |
18 October 2024 to 21 January 2027 |
In term |
No |
| Understanding the health needs of mothers involved in family court cases
DARS-NIC-196263-J9Q7Z |
7 |
1 |
21 December 2023 to 20 December 2026 |
In term |
No |
| Understanding and improving the use of investigations in primary care in patients subsequently diagnosed with cancer (ODR1920_196)
DARS-NIC-656863-R0V6Q |
2 |
0 |
20 December 2023 to 19 December 2026 |
In term |
No |
| Congenital Heart Audit: Measuring Progress In Outcomes Nationally (CHAMPION) aand LAUNCHES QI: Linking AUdit and National datasets in Congenital HEart Services for Quality Improvement.
DARS-NIC-234297-P4M5G |
8 |
98 |
18 December 2023 to 17 December 2026 |
In term |
No |
| Evaluation of aid to diagnosis for congenital dysplasia of the hip in general practice: controlled randomised trial
DARS-NIC-309509-L2G1J |
1 |
1 |
18 December 2023 to 17 December 2026 |
In term |
No |
| SABRE: Southall and Brent Revisited - Consented participants
DARS-NIC-148407-LRP3M |
9 |
81 |
11 December 2024 to 10 December 2026 |
In term |
No |
| SABRE: Southall and Brent Revisited - S251 participants
DARS-NIC-91374-Z5V6Y |
9 |
78 |
11 December 2024 to 10 December 2026 |
In term |
No |
| SABRE: Southall and Brent Revisited - S251 participants not cancer notifiable
DARS-NIC-99077-Q0K6Z |
8 |
35 |
11 December 2024 to 10 December 2026 |
In term |
No |
| Family, household and environmental risk factors for hospital admissions in childhood
DARS-NIC-234656-C3J1D |
3 |
14 |
25 October 2025 to 30 November 2026 |
In term |
No |
| Investigating the utility of machine learning methods to predict prognosis and guide treatment decisions for people with lung cancer (Lung-ORACLE)
DARS-NIC-678273-F2S0V |
8 |
9 |
26 September 2025 to 20 October 2026 |
In term |
No |
| MR1129 - SCORAD Feasibility Study
DARS-NIC-156409-W056Z |
6 |
0 |
19 October 2011 to 18 October 2026 |
In term |
No |
| PreHOspital Triage for potential stroke patients: lessONs from systems Implemented in response to COVID19 (PHOTONIC)
DARS-NIC-680546-S0V4K |
3 |
13 |
13 June 2025 to 9 October 2026 |
In term |
No |
| Advancing Survivorship after Cancer: Outcomes Trial (ODR1819_039)
DARS-NIC-656825-X7T4K |
1 |
1 |
6 October 2023 to 5 October 2026 |
In term |
No |
| Dose-response relationship between alcohol and suicide
DARS-NIC-287229-D6F9F |
1 |
0 |
12 September 2023 to 11 September 2026 |
In term |
No |
| Cancer Registry-wide study in infants with neuroblastoma; Task 11.4 of the ENNCCA Network of Excellence
DARS-NIC-656760-F8Y3C |
1 |
1 |
6 June 2025 to 20 August 2026 |
Expired |
No |
| Recording Antimicrobial Resistance during Death Certification in England
DARS-NIC-734773-Y3P3J |
3 |
9 |
8 August 2025 to 7 August 2026 |
Expired |
No |
| Modelling impact of interruptions to cancer screening with COVID ( ODR2021_016 )
DARS-NIC-656876-L4B0V |
2 |
0 |
3 May 2024 to 6 July 2026 |
Expired |
No |
| Linkage of NHS Digital data to young people with perinatal HIV, to monitor cancers and deaths.
DARS-NIC-368477-C9Q1X |
3 |
12 |
28 March 2025 to 27 March 2026 |
Expired |
No |
| Using Large-scale Routine Data to Monitor and Improve Ethnic Inequalities in Cancer and Cardiovascular Disease (ODR1920_301)
DARS-NIC-656874-T3L9D |
4 |
1 |
31 January 2025 to 8 February 2026 |
Expired |
No |
| Loneliness among people with 'Complex Emotional Needs' (CEN): A cross-sectional UK study
DARS-NIC-674976-S4T1V |
1 |
0 |
1 December 2023 to 31 January 2026 |
Expired |
No |
| UK Early Life Cohort Feasibility Study (ELC-FS)
DARS-NIC-482185-K8G0F |
3 |
10 |
28 March 2025 to 27 December 2025 |
Expired |
No |
| Prevalence, clinical characteristics and impact of body dysmorphic disorder in young people
DARS-NIC-259538-Q4V0W |
1 |
0 |
1 October 2022 to 30 September 2025 |
Expired |
No |
| Mental disorders and help seeking for mental or physical health conditions in sexual minorities
DARS-NIC-159576-C0V1M |
1 |
0 |
2 May 2022 to 1 May 2025 |
Expired |
No |
| The relationship between education and health outcomes for children and young people across England: the value of using linked administrative data.
DARS-NIC-27404-D5Z3F |
6 |
3 |
19 April 2022 to 18 April 2025 |
Expired |
No |
| Variation in Healthy Life Expectancy Throughout Childhood and Adulthood in England
DARS-NIC-06527-J1Q6T |
6 |
63 |
14 March 2022 to 13 March 2025 |
Expired |
No |
| Educational outcomes in children born after assisted reproductive technology; a population-based linkage study
DARS-NIC-258079-G7W1Y |
3 |
0 |
28 February 2022 to 27 February 2025 |
Expired |
No |
| A phase III, double blind, placebo controlled, randomised trial assessing the effects of aspirin on disease recurrence and survival after primary therapy in common non metastatic solid tumours ( ODR1718_261 )
DARS-NIC-656806-N9V7N |
8 |
0 |
15 January 2024 to 14 January 2025 |
Expired |
No |
| Precision in Provision: Predicting Treatment Outcome and Resource Use in Child Mental Health
DARS-NIC-140981-R5N6Z |
1 |
59 |
18 October 2021 to 30 September 2024 |
Expired |
No |
| The prevalence of mental illness and service use in people with borderline intellectual functioning compared to the general population.
DARS-NIC-177523-N8J2S |
1 |
0 |
26 May 2021 to 25 May 2024 |
Expired |
No |
| Research on Health and Ageing using English Longitudinal Study of Ageing (ELSA)
DARS-NIC-30493-Y0C0K |
8 |
0 |
22 April 2022 to 21 April 2024 |
Expired |
No |
| Creating synthetic data for health research
DARS-NIC-419453-G3G1G |
1 |
0 |
29 March 2021 to 28 March 2024 |
Expired |
No |
| A study exploring the relationships between cognitive and sensory disorders and experiences of abuse and discrimination
DARS-NIC-164594-K4C5N |
1 |
0 |
31 January 2022 to 28 February 2024 |
Expired |
No |
| Regional Heart Study (Female Cohort)
DARS-NIC-148101-R7RSL |
8 |
0 |
19 May 2023 to 30 November 2023 |
Expired |
No |
| Evaluating variation in special educational needs provision for children with Down syndrome and associations with emergency use of hospital care.
DARS-NIC-50975-X6N3J |
8 |
4 |
22 October 2020 to 21 October 2023 |
Expired |
No |
| MR1415 - Application for ONS mortality data to be used for flagging and analysis of the RADICALS trial, which is a large phase III randomised controlled trial for people with prostate cancer (ISRCTN 40814031).
DARS-NIC-37191-P5S9S |
6 |
28 |
2 August 2022 to 1 August 2023 |
Expired |
No |
| MR1090 - HiLo: Multicentre randomised trial of high dose versus low dose radioiodine
DARS-NIC-147936-1L3FD |
4 |
0 |
24 January 2022 to 25 January 2023 |
Expired |
No |
| Mixed methods evaluation of the Getting it Right First Time programme - improvements to NHS orthopaedic care in England
DARS-NIC-112374-X0T4S |
2 |
22 |
1 January 2022 to 31 December 2022 |
Expired |
No |
| Using national electronic databases to validate cardiovascular outcomes in PATCH – a pilot study to assess the use of electronic databases for clinical trial follow up.
DARS-NIC-242415-V9T5D |
2 |
20 |
6 December 2019 to 5 December 2022 |
Expired |
No |
| MR1213 - Lung-SEARCH: A RANDOMISED CONTROLLED TRIAL OF SURVEILLANCE FOR THE EARLY DETECTION OF LUNG CANCER...
DARS-NIC-147948-6MSGP |
6 |
17 |
1 November 2021 to 31 October 2022 |
Expired |
No |
| Evaluating protocols for identifying and managing patients with FH
DARS-NIC-300282-G9Q0Q |
8 |
1 |
1 November 2019 to 31 October 2022 |
Expired |
No |
| Variation in avoidable hospital admissions by mental health status
DARS-NIC-167186-V7J4F |
3 |
0 |
7 March 2019 to 6 March 2022 |
Expired |
No |
| MR1396 - GALA-5: An Evaluation of the Tolerability and Feasibility of combining 5-Amino-Levulinic Acid (5-ALA) with Carmustine Wafers (Gliadel) in the Surgical Management of Primary Glioblastoma.
DARS-NIC-03422-Y7Y0Z |
2 |
0 |
1 April 2018 to 31 March 2021 |
Expired |
No |
| MR623 - NATIONAL MOTHER AND CHILD COHORT
DARS-NIC-148128-815J1 |
4 |
0 |
2 November 2020 to 3 March 2021 |
Expired |
No |
| Critical Care Health Informatics Collaborative
DARS-NIC-27803-W8G1B |
2 |
26 |
2 July 2020 to 12 February 2021 |
Expired |
No |
| MR241 - GROWTH HORMONE THERAPY
DARS-NIC-147875-00SJY |
4 |
0 |
13 August 2020 to 30 December 2020 |
Expired |
No |
| MR104C - British Women's Heart and Health Study (s251 cohort)
DARS-NIC-174486-Q8J1B |
3 |
0 |
1 April 2020 to 19 November 2020 |
Expired |
No |
| ‘Usual Care’ versus ‘Specialist Integrated Care’: A Study of Hospital Discharge Arrangements for Homeless People in England
DARS-NIC-86666-V7Z1L |
4 |
0 |
1 December 2019 to 1 November 2020 |
Expired |
No |
| Small area geodemographic profiling of health needs
DARS-NIC-28051-Q3K7L |
1 |
0 |
1 March 2018 to 30 September 2020 |
Expired |
No |
| Acute Day Units as Crisis Alternatives to Residential Care
DARS-NIC-93084-W4B4L |
4 |
27 |
1 October 2017 to 30 September 2020 |
Expired |
No |
| MR688 - UK Ductal Carcinoma in Situ (DCIS) Trial
DARS-NIC-148348-XTNPJ |
6 |
0 |
10 September 2010 to 9 September 2020 |
Expired |
No |
| MR1291: Clinical Cohorts in Coronary Disease Collaboration (4C)
DARS-NIC-152228-DL5MK |
4 |
0 |
17 March 2017 to 7 February 2020 |
Expired |
No |